Regenerative Biotechnology
Gencell® Mesenchymal Stem Cells
Pre-stimulated mesenchymal stem cells for pulmonary therapeutic support.
Injectable solution of mesenchymal stem cells with enhanced ACE-2 expression, designed to modulate inflammation, protect endothelial tissue, and support pulmonary recovery in SARS-CoV-2 infection.
Composition
Mesenchymal stem cells.
Pharmaceutical form
Injectable solution.
Presentation
Single-dose vial, 4 ml.
Therapeutic properties
Promote tissue repair through immunomodulation, inhibition of apoptosis, stimulation of cellular proliferation, and release of soluble ACE-2, contributing to immune regulation, endothelial protection, and pulmonary recovery.
- Reduction of pulmonary inflammation.
- Immune response modulation.
- Inhibition of cellular apoptosis.
- Stimulation of tissue regeneration.
- Transdifferentiation at injury site.
- Release of soluble ACE-2.
- Reduction of viral internalization.
- Protection of pulmonary endothelium.
Mechanism of action & Clinical data
Migrate to injured tissue, modulate inflammation, inhibit apoptosis, stimulate regeneration, and release soluble ACE-2 that reduces SARS-CoV-2 internalization.
Indication: adjunct therapy in active SARS-CoV-2 infection and acute respiratory distress syndrome secondary to COVID-19.
Indications
Adjunct therapy in active SARS-CoV-2 infection and acute respiratory distress syndrome secondary to COVID-19.
Administration
Intravenous administration via slow infusion diluted in 0.9% saline solution. No bolus.
Contraindications
Hypersensitivity to ACE-2 inhibitors or any component of the formula. Diagnosis of neoplasia.
Storage
Store refrigerated between 2–8 °C. Protect from direct sunlight. Do not freeze.
