Regenerative Biotechnology
Chondromatrix
Autologous chondrocyte implant in a collagen matrix for advanced regeneration of knee articular cartilage.
Chondromatrix is an advanced tissue engineering solution based on the implantation of autologous chondrocytes cultured in vitro and seeded onto a collagen matrix, enabling articular cartilage regeneration with structural properties similar to hyaline cartilage.
Composition
5 million autologous chondrocytes per cm² in collagen matrix.
Pharmaceutical form
Collagen membrane with autologous chondrocytes for surgical implantation.
Presentation
Membranes in various sizes, adjustable to the defect, ready for arthroscopic or open implantation.
Mechanism of action & Clinical data
Chondrocytes adhere to the cartilage lesion promoting tissue regeneration, improving mechanical strength, elasticity, and shock absorption of the treated joint.
Indications
Full-thickness focal cartilage defects of the knee of traumatic or degenerative origin.
Administration
Surgical implantation via arthroscopic or open surgery followed by controlled rehabilitation.
Contraindications
Allergy to antibiotics, joint infections, pregnancy, breastfeeding, and advanced osteoarthritis.
Storage
Refrigerate between 2–8 °C. Use immediately upon receipt. Do not freeze.
