Regenerative biotechnology
Gencell® CTM Metformina IA
Mesenchymal stem cells pretreated with metformin for localized joint and bone repair.
Injectable solution of mesenchymal stem cells pretreated with metformin, designed to promote joint repair, bone regeneration, and inflammatory modulation through targeted intra-articular administration.
Composition
Mesenchymal stem cells pretreated with metformin.
Pharmaceutical form
Injectable solution.
Presentation
Monovette with 4 ml.
Therapeutic Properties
They promote joint repair through local immunomodulation, inhibition of apoptosis, stimulation of cellular proliferation, chondrogenic and osteogenic transdifferentiation, improvement of tissue energy metabolism, and reduction of joint inflammation.
- Reduction of local joint inflammation.
- Reduction of joint pain.
- Inhibition of apoptosis in cartilage.
- Stimulation of chondral regeneration.
- Promotion of bone regeneration.
- Promotes fracture consolidation.
- Repair of connective tissues.
- Improvement of joint functionality.
Mechanism of action & Clinical data
They integrate into the joint environment, modulate inflammation, inhibit apoptosis and, via OCT-1, increase GLUT2/GLUT4, promoting bone and chondral regeneration and local energy metabolism.