Regenerative biotechnology
Gencell® Metabolic CTM
Mesenchymal stem cells pretreated for metabolic and lipid support.
Injectable solution of mesenchymal stem cells pretreated with evolocumab, aimed at modulating inflammation, repairing the endothelium, and promoting regulation of lipid metabolism in dyslipidemias.
Composition
Mesenchymal stem cells pretreated with evolocumab.
Pharmaceutical form
Injectable solution.
Presentation
Monovette with 4 ml.
Therapeutic Properties
They promote tissue repair through immunomodulation, reduction of inflammation, inhibition of apoptosis, stimulation of cellular proliferation, and improvement of lipid homeostasis through PCSK9 inhibition.
- Modulation of systemic inflammation.
- Regulation of LDL cholesterol.
- Protection of the vascular endothelium.
- Inhibition of cellular apoptosis.
- Stimulation of tissue regeneration.
- Improvement of lipid profile.
- Reduction of endothelial damage.
- Support for metabolic homeostasis.
Mechanism of action & Clinical data
They migrate to injured tissue, modulate inflammation, inhibit apoptosis and, through PCSK9 inhibition, increase LDL uptake and promote endothelial regeneration.
Indications
Adjunct in the treatment of familial hypercholesterolemias and mixed dyslipidemias.
Administration
Intravenous route via slow infusion diluted in 0.9% saline solution, without bolus.
Contraindications
Sensitivity or allergy to formula components. Diagnosis of neoplasia.
Storage
Store refrigerated between 2 and 8 °C, protected from direct sunlight. Do not freeze.
